When Grammy-nominated singer-songwriter Aloe Blacc got COVID despite being vaccinated and boosted, he tried to fund research for a better solution. What he quickly found out? You can’t just write a check in biotech. Regulators require a commercialization plan, and philanthropy doesn’t move science through clinical trials or get you a license on university IP. Now, he’s bootstrapping a cancer drug platform targeting pancreatic cancer, a disease that […]

When an 82-year-old Kentucky woman was offered $26 million from an AI company that wanted to build a data center on her land, she said no. Sure, that same company can try to rezone 2,000 acres nearby anyway, but as AI infrastructure stretches further into the real world, the real world is starting to push back.  That tension is everywhere […]

Over the past few years, a new category of mobile apps has quietly exploded into a multi-billion dollar business. They’re called “micro dramas” — short-form, mobile-first scripted shows designed to be watched vertically on your phone. Think soap opera meets TikTok, complete with secret billionaire romances, disapproving werewolf mothers-in-law, and cliffhangers engineered to keep users tapping. The leading […]

CEO Jensen Huang took the stage at Nvidia’s GTC conference this week in his signature leather jacket to deliver a two-and-a-half-hour keynote, projecting $1 trillion in AI chip sales through 2027, declaring that every company needs an “OpenClaw strategy,” and closing with a rambling Olaf robot that had to get its mic cut. The message was hard to miss: Nvidia […]

Artificial intelligence models are multiplying fast, and competition is stiff. With so many players crowding the space, which one will be the best — and who decides that? Arena, formerly LM Arena, has emerged as the de facto public leaderboard for frontier LLMs, influencing funding, launches, and PR cycles. In just seven months, the startup went from a UC Berkeley PhD research […]

According to Index Ventures Partner Shardul Shah, cybersecurity startup Wiz sits “at the center of three tailwinds: AI, cloud, and security spend.” Those tailwinds powered what just became the largest venture-backed acquisition in history — Google’s $32 billion deal, finalized after a declined 2024 offer, antitrust review on both sides of the Atlantic, and an […]

For years, venture capitalists have been skeptical of beverage startups, citing thin margins and brutal distribution as reasons most brands never break out. But a new wave of “functional soda” companies has been challenging that assumption, including Poppi, the prebiotic soda brand that grew from a kitchen experiment into a $1.95 billion acquisition by PepsiCo.  On this episode of […]

The Pentagon has officially designated Anthropic a supply-chain risk after the two failed to agree on how much control the military should have over its AI models, including its use in autonomous weapons and mass domestic surveillance. As Anthropic’s $200 million contract fell apart, the DoD turned to OpenAI instead, which accepted and then watched ChatGPT uninstalls surge 295%. As the stakes keep rising, the question remains: how much unrestricted […]

Does a consumer hardware company need to get on the VC treadmill to succeed? Eleven years and 290 million products sold across 115 countries later, PopSockets has proven that the bootstrapped, low-dilution path more viable than the industry gives it credit for. The global consumer hardware brand was built on less than $500k, no institutional capital, and a philosophy professor’s determination.  Watch as founder and former CEO […]

Crypto is creeping back into the startup conversation, but at ETHDenver last week, the buzz was as much about Washington as it was about tokens. Policy shifts are rippling through the market as Tether and stablecoins face scrutiny, players like Stripe re-enter the conversation, and startups either find traction or flame out. The hype cycle is over, or at least taking a break. So what comes next?  On […]

The creator economy is evolving fast, and ad revenue alone isn’t cutting it anymore. YouTubers are launching product lines, acquiring startups, and building actual business empires. In fact, MrBeast’s company bought fintech startup Step, and his chocolate business is outearning his media arm. This isn’t just one creator’s strategy. For many, it’s the new playbook.  On this episode of TechCrunch’s Equity podcast, hosts Kirsten Korosec, Anthony Ha, and Rebecca Bellan unpack how creators are diversifying beyond ads, […]

Startup founders are being pushed to move faster than ever, using AI while facing tighter funding, rising infrastructure costs, and more pressure to show real traction early. Cloud credits, access to GPUs, and foundation models have made it easier to get started, but those early infrastructure choices can have unforeseen consequences once startups move beyond […]